Biography of Chief Massasoit, Native American Hero

Biography of Chief Massasoit, Native American Hero Chief Massasoit (1580–1661), as he was known to the Mayflower Pilgrims, was the leader of the Wampanoag tribe. Also known as The Grand Sachem as well as Ousemequin (sometimes spelled Woosamequen), Massasoit played a major role in the success of the Pilgrims. Conventional narratives of Massasoit paint the picture of a friendly Native American who came to the aid of the starving Pilgrims- even joining them in what is considered the first Thanksgiving feast- for the purpose of maintaining peaceful relationships and harmonious co-existence. Fast Facts: Known For: Leader of the Wampanoag tribe, who helped the Mayflower PilgrimsAlso Known As: The Grand Sachem, Ousemequin (sometimes spelled Woosamequen)Born: 1580 or 1581 in  Montaup, Bristol, Rhode IslandDied: 1661Children: Metacomet,  WamsuttaNotable Quote: What is this you call property? It cannot be the earth, for the land is our mother, nourishing all her children, beasts, birds, fish and all men. The woods, the streams, everything on it belongs to everybody and is for the use of all. How can one man say it belongs only to him? Early Life Not much is known about Massasoits life before his encounters with the European immigrants other than he was born in Montaup (now Bristol, Rhode Island) around 1580 or 1581. Montaup was a village of the Pokanoket people, who later became known as the Wampanoag. By the time of the Mayflower Pilgrims interactions with him, Massasoit had been a great leader whose authority extended throughout the southern New England region, including the territories of the Nipmuck, Quaboag, and Nashaway Algonquin tribes. Colonists Arrival When the Pilgrims landed in Plymouth in 1620, the Wampanoag had suffered devastating population losses due to a plague brought by Europeans in 1616; estimates are that upwards of 45,000, or two-thirds of the entire Wampanoag nation, had perished. Many other tribes had also suffered extensive losses throughout the 15th century due to European diseases. The arrival of the English with their encroachments on Indian territories combined with the depopulation and the Indian slave trade, which had been underway for a century, led to increasing instability in tribal relationships. The Wampanoag were under threat from the powerful Narragansett. By 1621, the Mayflower Pilgrims had lost half of their original population of 102 people as well; it was in this vulnerable state that Massasoit as the Wampanoag leader sought alliances with the equally-as-vulnerable pilgrims. The Pilgrims were impressed with Massasoit. According to MayflowerHIstory.com, Plymouth colonist Edward Winslow described the chief as follows: In his person he is a very lusty man, in his best years, an able body, grave of countenance, and spare of speech. In his attire little or nothing differing from the rest of his followers, only in a great chain of white bone beads about his neck, and at it behind his neck hangs a little bag of tobacco, which he drank and gave us to drink; his face was painted with a sad red like murry, and oiled both head and face, that he looked greasily. Peace, War, and Protection When Massasoit entered into a treaty of mutual peace and protection with the pilgrims in 1621, there was more at stake than a simple desire to make friends with the newcomers. Other tribes in the region were entering into agreements with the English colonies as well. For example, the Shawomet Purchase (todays Warwick, Rhode Island), in which sachems Pumhom and Sucononoco claimed they had been forced to sell under duress a large tract of land to a rogue Puritan group under the leadership of Samuel Gorton in 1643, led to tribes placing themselves under the protection of the Massachusetts colony in 1644. By 1632, the Wampanoags were engaged in a full-scale war with the Narragansett. Thats when Massasoit changed his name to Wassamagoin, which means Yellow Feather. Between 1649 and 1657, under pressure from the English, he sold several large tracts of land in Plymouth Colony. After abdicating his leadership to his eldest son Wamsutta (aka Alexander), Massasoit is said to have gone to live the rest of his days with the Quaboag who maintained the highest respect for the sachem. Later Years and Death Massasoit is often held up in American history as a hero because of his alliance and assumed love for the English, and some of the documentation hints at an overestimation of his esteem for them. For example, in one story when Massasoit contracted an illness in March 1623, Plymouth colonist Winslow is reported to have come to the side of the dying sachem, feeding him comfortable conserves and sassafras tea. Upon his recovery five days later, Winslow wrote that Massasoit said that the English are my friends and love me and that whilst I live I will never forget this kindness they have showed me. However, a critical examination of the relationships and realities casts some doubt over Winslows ability to heal Massasoit, considering the Indians superior knowledge of medicine and likelihood that the sachem was being attended to by the tribes most skilled medicine people. Still, Massasoit lived for many years after this illness, and he remained a friend and ally of the Mayflower Pilgrims until his death in 1661. Legacy Peace between the Wampanoag Nation and the Pilgrims lasted for four decades after the 1621 treaty, and centuries after his death, Massasoit has not been forgotten. For more than 300 years, Massasoit, and many artifacts related to his time as chief were buried in Burr’s Hill Park, which overlooks Narragansett Bay in the present-day town of Warren, Rhode Island. A confederation of Wampanoags, who still live in the area, worked for two decades to secure funding and dig up Massasoits remains and the remains and artifacts of many other Wampanoag tribe members who were buried in Burrs Hill. On May 13, 2017, the confederation re-interred the remains and items in the park in a concrete vault marked with a simple boulder during a solemn ceremony. They hope the burial site will eventually be added to the National Register of Historic Places. Ramona Peters, the repatriation coordinator of the Wampanoag Confederation who led the project, explained shortly before the re-interment: I would hope Americans would be interested too. Massasoit made it possible for the colonization of this continent. Sources Daley, Jason. â€Å"Massasoit, Chief Who Signed Treaty With the Pilgrims, To Be Reburied.†Ã‚  Smithsonian.com, Smithsonian Institution, 21 Apr. 2017.Hayes, Ted. â€Å"Burrs Hill Re-Burial to Be Solemn, Private Affair.†Ã‚  RhodyBeat, 12 May 2017.â€Å"Massasoit.†Ã‚  MayflowerHistory.com.â€Å"Massasoit Quotes. AZ Quotes.

The role of microRNAs in breast cancer Essay Example | Topics and Well Written Essays - 1750 words

The role of microRNAs in breast cancer - Essay Example Below is a description of the effect of miRNAs in breast cancer metastasis, treatment and cause. Regulation on Cancer Causing Proteins According to Yamashita and others, mis-expressions or mutations in miRNA have been associated with different types of human cancers. The loss-or-gain-of function of some miRNAs has also been found to contribute to tumorigenesis and epithelial cellular transformation of the breast. Research has also revealed that profiling of miRNA expression shows that different molecular subtypes in breast cancer have different expressions of miRNAs (Yamashita et al, n.d., p. 331). ER? is responsible for breast cancer. There are two types of ER? related breast cancers. There are ER?-negative and ER?-positive breast cancers. Most primary breast cancers express ER? with an approximate value of 70%. ER?-positive breast cancers have been found to respond positively to endocrine therapy. This could be because of the role of ER? in the endocrine system. ER? is necessary fo r estrogen-dependent growth. It affects the response to endocrine therapy among women with ER?-positive breast cancers depending on its level of expression. ... 331). The Roles of miRNAs in Cellular Processing There are various cellular processes in which miRNAs are involved. These include development of skeletal and heart muscles, and establishment and maintenance of cell lineage. The miRNAs have the ability to express specific tissue, which has been, observed in insulin secretion, proliferation, hematopoiesis, adepocyte development, apoptosis, and brain pattering. Because of these roles and involvement in diverse cellular functions, miRNAs’ function and expression dysregulation has the potential to cause diseases. This has been observed in Tourette’s syndrome, fragile X syndrome, and from recent research studies, associated with cancer development and progression (Kayani, Kayani, Malik & Faryal, 2011, p. 3175). Bachour and Bennett (2011) also note that miRNAs are involved in regulation of apoptosis, proliferation and differentiation, and have the ability to directly obstruct stability and translation of specific gene transcri pts that they target and cause cell physiology disorder. In breast cancer, for example, miRNAs have been found to be involved in the dysregulation of tumor suppressor genes and oncogenes, causing progression of breast cancer (Bachour & Bennett, 2011; Liu et al, 2011). MiRNAs are also found in regulation of cell development and cell cycle. This characteristic places them in the best place for exploring anticancer treatments. Altered miRNA signatures cause breast cancer metastasis and development. This has been identified through the study of the effect of the loss of tumour suppressor miRNAs such as miR-31, miR-203, miR-30a, miR-34a, miR-200s, miR-205, miR-342, miR-125s, miR-206, and let-7s, or the over-expression of oncogenic miRNA such as miR-21, miR-155, miR-222, miR-10b,

MPH502-Introduction to Public Health (Module 3 CBT) Essay

MPH502-Introduction to Public Health (Module 3 CBT) - Essay Example Right from the early days of industrial revolution, substantial portions of rural population together with migrants coming in search of work from other countries flocked to cities and towns that resulted in overcrowding, slum conditions and squalor with the associated problems of garbage, sewage, pollution and unclean drinking water that had negative impact on public health. Citizens quite rightly veered round to the opinion that control of diseases and maintenance of public health should fall in the public domain of governmental responsibility and there should be relevant laws and regulations that would ensure each citizen gets the chance to lead a healthy life with government being responsible to provide all the necessary amenities and maintain decent standards of public health. Governments of both industrialized and developing countries have since then passed numerous legislations in this regard and public health is quite rightly now firmly entrenched in the domain of public autho rity and public administration. Neither the governments nor the citizens deny that the primary responsibility of public health rests with the government of the country. Public health professionals quite obviously desire that there should be progressively larger allocation of funds towards prevention of diseases rather than fighting them when they threaten to go out of hand and become a matter of serious concern. Prevention, as the saying goes, is always better than cure. But in the political climate prevailing in late and middle 1990s it was becoming increasingly difficult for public health professionals to emphasize the importance of prevention as some of the law makers were of the opinion that the threat to public health was made to look more sinister than it actually was. Though there might be some instances of such overdrive, one agrees wholeheartedly with the author’s concern about prevention of a disease before it snowballs into a public health crisis. (Gostin L. O.,

Candidate Set Essay Example for Free

Candidate Set Essay Part of the fast changing science of database management is the improvement of association rules generation. Several algorithms had been proposed and implemented in different platforms or programs to generate these rules. These rules state the rate of confidence of predicting an occurrence of entity or an event based on the occurrence of another entity or event. One popular algorithm proposed to generate the association rules of a given data is the Apriori Algorithm. It uses the bottom-up approach in order to come up with all the significant association rules by specifying the minimum support a super set must have. With the help of a pruning step that uses the property of infrequent set defined in the paper Fast Algorithms for Discovering the Maximum Frequent Set [Lin98], the database scans needed to obtain the MFS are minimized. Another algorithm to solve the maximum frequent sets is the top-down approach. Its first main aim is to discover the Maximum Frequent Candidate Set (MFCS) that would quickly gives all the other frequent set based on the property of frequent sets. Here in this paper, we would compare the disadvantages to be encountered on both algorithms and how the integration of the two cited algorithms would work and be implemented. Apriori Algorithm’s Dilemma FIGURE 2. 1: Lattice 1, 2, and 3 resembling the discovery of frequent set [Dun03]. PROPERTY 1: If an item set is infrequent, all its superset must be infrequent, and they do not need to be examined further. Apriori Algorithm needs to check the entire super sets with one element, {A}, {B}, {C}, and {D}, in order to know the MFCS. With the help of the pruning step that use the above stated property of infrequent sets then in Figure 2. 1 we could determine the MFCS of the universe ABCD by performing Apriori Algorithm. In Figure 2. 1 we should perform four database scans checking the super sets A, B, C and D respectively before we could determine the MFCS for all lattices in Figure 2. 1. Lattice 1 needs four database scans before determining that A is the MFCS. Lattice 2 needs four scans in order to determine ACD and this would be the same in lattice 3 which needs four scans before we would conclude that ABCD is the MFCS. What if we would consider a lattice with 5 items, with 6 items and so on? We would then come up with the conclusion that Apriori Algorithm needs to have n database scans for n items. By considering the above fact, try to examine the lattice of ABCDEFGHIJKLMNOP QRSTUVWXYZ. Then we would conclude that MFCS would be determined after 28 database scans through the use of Apriori Algorithm. The Top-down Approach and the MFCS The top-down approach works well when the MFCS is long. What if the database to be examined has up to 100 items? Then, in Apriori Algorithm, it needs to have 100 database scans in order to come up with the MFCS. On the contrary, the Top-down approach starts with the set containing all the elements of the item set considered down to its subsets. In Figure 2. 1 the Top-down approach checks first the frequency of ABCD, BCD, and so on. What is better with the Top-down Approach compared to the Apriori Algorithm is that it only needs to know the first occurrence of a frequent set to get the MFCS. This is because of the second property of frequent sets. PROPERTY 2: If an item set is frequent, all its subsets must be frequent and they do not need to be examined further. Let’s examine the performance of top-down approach for the three lattices in Figure 2. 1. Top-down approach works best when all of the items in the item set are all frequent. In lattice 3, Top-down approach needs only one database scan in order to come up with the complete frequent sets. Lattice 3’s MFCS is ABCD, therefore it would consider all the subsets of ABCD because ABCD is frequent in the first place. But the problem with the top-down approach is when the MFCS is short. On lattice 3, the number of database scans needed to know MFCS is still lower than the number of database scans needed in the Apriori algorithm, three as compared to four. But on the case of the lattice three, the Top-down approach needs to traverse all the points in the lattice in order to determine the MFCS which is A. The table below gives a view of the database scans needed to determine the complete MFS. Table 2. 1 Apriori and Top-down Approach Comparison Items Apriori Top-down Approach Best case:1 Worst case: 15 5 5 Best case: 1 Worst case: 31 . . . n n Best case: 1 Worst case: 2n 1 Upon considering both the advantages and disadvantages of the two above discussed algorithms, I had decided to merge the good side properties of the two algorithms. To come up with an integrative algorithm that would make use of the concepts of the Apriori Algorithm and Top-down approach, we should first understand or simulate how the two algorithms come up with generating their set of possible candidates for frequent sets. Here is a program code that would generate Apriori Algorithm’s set of possible candidates given the starting candidate {0} and the number of items to be considered. Note that I had opted to start the representation of the possible candidates with zero because the Java program that I had decided to use in order to perform the discussed algorithms uses zero as its start index on its array data structures. Accompanying this program code is the explanation of how did the recursive property come up with the set of possible candidates.

Essay --

â€Å"You Learn Something New Every Day† Bud Blake, ‘Tiger’ (1918-2005) This comical strip of art created by â€Å"the genial cartoonist whose ‘Tiger’ comic strip was adored worldwide† (King Features, 2005) raises many important and striking questions. Although we have a general idea of what learning means, do we know its true definition? Do we understand its significance, its inevitable role in our everyday lives from the moment of birth? The old adage says â€Å"You learn something new every day†. So does that mean that learning is a continuous process? Or does it only happen in a classroom or a lecture room? How does learning happen? Is it a voluntary process or involuntary, conscious or unconscious? However, defining learning and explaining the various learning theories alone, does not provide enough accuracy or truthfulness when applying the theory to third-level students. It is vital to keep in mind who the modern Irish third-level student is as the interpretations may vary. The 21st century presents students of all diffe rent shapes and sizes, with various abilities and backgrounds. This essay will examine theories behind the phenomenon of learning in an attempt to draw up a vivid explanation of what it is, how it works and how it can be applied to a modern Irish third-level student. So what is learning? Well, it can be understood as â€Å"a relatively permanent change in behaviour that is brought about by experience† (Feldman, 2010) or â€Å"just a matter of creating associations among ideas as a direct result of experience† (Gleitman, Gross and Reisberg, 2010). Many other educational psychologists define learning as â€Å"the achievement of greater proficiency, mastery and fluency in a person’s capacity to know or do something that they were previo... .... Clearly, not all behaviour observed is repeated. If a satisfactory reward follows a behaviour, it will be repeated. If there is a punishment for carrying out a behaviour, chances are, it will not reoccur. Observational learning is really common third level education. If a student sees his friend study well, attend all lectures and tutorials and get rewarded with good grades and increased motivation, that student will be encouraged to do the same. Undeniably, no two people are the same. We all differ in one way or another, including in how we learn. We are born with different abilities and brought up in different circumstances through which the values of learning are passed on to us. Therefore, some students are more motivated to succeed than others. For example voluntary immigrant students perform better than those who are involuntary immigrants (Feldman, 2011).

Manifestations of vandalism Essay

Some say that the youths of today are irresponsible. This view merits consideration because it is debatable. Nowadays, vandalism become a trend around the teenagers. According in the Oxford Dictionary vandalism means a destruction by vandals. This vandalism has become a culture for the teenagers. This issue is making a country so ashamed towards the others country. There are many factors, effect and resolution for this issue. We must take a action to reduce this vandalism among the teenagers. Teenagers are the product of a community system. Dysfunctional society will eventually produce a flawed product. Attitude of some people now who cared more about materialistic and indifferent to social issues certainly complicate the existing problem. According to many studies vandalism occurred in the city. Youth scribbling and damaging public property rather than not educated but the generation born in the city is difficult to control. In urban areas some people do not care for what is happening around them. By the youth feel that they are free to pursue this regardless of the negative symptoms of a sense of responsibility towards public property. Vandalism activities also have adverse effects on society. Activity causing vandalism of public property such as public telephones and so destroyed. It will be difficult for the community if they had to use public facilities for emergency purposes. Vandalism is often underestimated by the local community. They just sit back while the vandalism happened in front of their eyes. Finally people also suffer from the heinous activities. Community is difficult to make contact during emergency situations. Example public phones damaged during house is on fire. In addition, the community is not comfortable while using other public property. Example wet while waiting for the bus because the bus stop damaged roof could not stop because of the rain. Graffiti on the walls of public toilets worsen and encourage the younger generation to emulate these unhealthy symptoms. In addition, vandalism activities also affect the country. Vandalism activities cause and affect the country’s image tarnished Malaysia’s economic position. This is due to the lack of the arrival of tourists from outside to Malaysia because of the bad environment and attitudes of the  people who do not care. In effect, the country’s tourism industry will decline. Industries in tourism is among the contributors to the country’s economic position. Decline in tourism caused by losses due to unemployed people had to repair and improve infrastructure and public facilities have been destroyed. Read more:  Causes of Vandalism Essay Many vandalism phenomena that can affect the eye can see and this certainly affects the image of the country. Total losses due to this vandalism is enormous. Allocation of funds used for refurbishing and repairing damaged facilities is better if used for other projects that are more beneficial. This course will benefit the nation as a whole. There are many factors of being this vandalism among the teenagers. The first factors is peer influence. Peer influence can lead to vandalism. Teenagers usually easier to copy and influence by their peers. Peer influence will shape the attitudes, values and behaviours among the youth, especially youth who have dropped out and family problem. Usually, teenagers who commit vandalism is a teenager in the group, they do not have a purpose and when gathered arise include scribbling ideas and damaging public property. Peer influence also make the teenagers become incautious about their studies and not focus about their education. Moreover, parenting and family also one of the factors of being the vandalism among the teenagers. Parents are the impetus for the nature of vandalism among teenagers. For example, when driving parents littering or skin of fruits such as rambutan and oranges while ignoring the speed limit signs. Some teenagers who get caught in symptom vandalism comes from troubled families or families that practice negative life. According to a study carried out revenge vandalism by teenagers who want to be free and a troubled family background. Besides lack of proper control and guidance of parents also among the main factor influence youth stuck in negative symptoms. Therefore, the measures to overcome the problem of vandalism among teenagers should be implemented immediately.First of all, parents should carry out an important role in cleaning up the vandalism. They need to monitor the activities of their children so as not slipping into the negative. Not only that, but mixing children should also be monitored in order to not make a mistake in choosing a partner. Moreover, parents should inculcate in themselves divinity children since childhood. This is so because of religious knowledge can become a major fortification in preventing young people from influenced by negative elements like  vanadalisme activities. If parents fulfill their roles properly, definitely vandalism can be easily overcome. Furthermore, role of society and the school should have to help this issue to reduce the vandalism among the teenagers. Every member of society should be concerned about and pay attention to their children not to do this wrong, and people should be aware of what is happening around them. Community needs to be proactive against vandalism symptoms that occur in their area. In addition members of the community can play a vital role to provide an understanding of how bad moral vandalism. The school should provide advice and guidance to students about the importance of public property. Younger generation should be explained in detail about their responsibility for public property. Explain to students what their feelings if their school bags defaced or torn by irresponsible people such awareness will partly reflect the importance of attitude and responsibility. Therefore, all parties, particularly the parents, the community, the government and schools should work together and carry out their obligations in order to reduce the symptoms of this increasingly serious. If the intention is successfully implemented, it is possible our country can stand, sit low in developed countries. Hopefully, with this solution, we are able to realize the Vision 2020 and is famous the world over.

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